Status | Study |
Active, not recruiting |
Study Name: Early Biomarkers of Autism in Infants With Tuberous Sclerosis Complex (TSC) Condition: Tuberous Sclerosis Complex Date: 2013-01-28 |
Active, not recruiting |
Study Name: A Placebo-controlled Study of Efficacy & Safety of 2 Trough-ranges of Everolimus as Adjunctive Therapy in Patients With Tuberous Sclerosis Complex (TSC) & Refractory Partial-onset Seizures Condition: Tuberous Sclerosis Complex-associated Refractory Seizures Date: 2012-10-09 Interventions: Drug: RAD001 Other Name: Afini |
Completed |
Study Name: Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC) Condition: Tuberous Sclerosis Complex Date: 2011-02-02 Interventions: Drug: RAD001 RAD001 is formulated as tablets of 5.0 mg str |
Completed |
Study Name: Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC) Condition: Epilepsy Tuberous Sclerosis Complex Date: 2010-02-15 Interventions: Drug: Everolimus Everolimus is available in tablet form. The starting dose will be 5 mg/m2/day, rounded |
Completed |
Study Name: Long Term Follow Up for RAD001 Therapy of Angiomyolipomata in Patients With Tuberous Sclerosis (TSC) and Sporadic Lymphangioleiomyomatosis (LAM) Condition: Tuberous Sclerosis Angiolipoma Date: 2008-11-17 Interventions: Drug: everolimus (RAD001) Subjects will resume the dosing regimen that they were receiving at the comple |
Completed |
Study Name: Efficacy and Safety of Everolimus (RAD001) in Patients of All Ages With Subependymal Giant Cell Astrocytoma Associated With Tuberous Sclerosis Complex (TSC)(EXIST-1) Condition: Tuberous Sclerosis Subependymal Giant Cell Astrocytoma Date: 2008-11-12 Interventions: Drug: Everolimus Everolimus wa |
Completed |
Study Name: Efficacy and Safety of RAD001 in Patients Aged 18 and Over With Angiomyolipoma Associated With Either Tuberous Sclerosis Complex (TSC) or Sporadic Lymphangioleiomyomatosis (LAM) Condition: Tuberous Sclerosis Complex (TSC) Lymphangioleiomyomatosis (LAM) Date: 2008-11-10 Interventions: Drug: Everolimus (RAD001) Ever |
Completed |
Study Name: Tuberous Sclerosis Complex Natural History Study: Renal Manifestations Condition: Tuberous Sclerosis Complex Date: 2007-12-27 |
Active, not recruiting |
Study Name: Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM Condition: Tuberous Sclerosis Lymphangioleiomyomatosis Date: 2007-06-21 Interventions: Drug: sirolimus daily oral sirolimus with dosage individualised by trough blood levels |
Completed |
Study Name: Rapamycin Therapy for Patients With Tuberous Sclerosis Complex and Sporadic LAM Condition: Tuberous Sclerosis Lymphangioleiomyomatosis Date: 2007-04-06 Interventions: Drug: Rapamycin, sirolimus |